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The Rho kinases I and II regulate different aspects of myosin II activity

The homologous mammalian rho kinases (ROCK I and II) are assumed to be functionally redundant, based largely on kinase construct overexpression. As downstream effectors of Rho GTPases, their major substrates are myosin light chain and myosin phosphatase. Both kinases are implicated in microfilament...

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Detalles Bibliográficos
Autores principales: Yoneda, Atsuko, Multhaupt, Hinke A.B., Couchman, John R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171463/
https://www.ncbi.nlm.nih.gov/pubmed/16043513
http://dx.doi.org/10.1083/jcb.200412043