Essential role of CIB1 in regulating PAK1 activation and cell migration

p21-activated kinases (PAKs) regulate many cellular processes, including cytoskeletal rearrangement and cell migration. In this study, we report a direct and specific interaction of PAK1 with a 22-kD Ca(2+)-binding protein, CIB1, which results in PAK1 activation both in vitro and in vivo. CIB1 binds...

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Detalles Bibliográficos
Autores principales: Leisner, Tina M., Liu, Mingjuan, Jaffer, Zahara M., Chernoff, Jonathan, Parise, Leslie V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171473/
https://www.ncbi.nlm.nih.gov/pubmed/16061695
http://dx.doi.org/10.1083/jcb.200502090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171473/
https://www.ncbi.nlm.nih.gov/pubmed/16061695
http://dx.doi.org/10.1083/jcb.200502090

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