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Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca(2+)/calmodulin

The Ras/MAPK pathway regulates synaptic plasticity and cell survival in neurons of the central nervous system. Here, we show that KRas, but not HRas, acutely translocates from the plasma membrane (PM) to the Golgi complex and early/recycling endosomes in response to neuronal activity. Translocation...

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Detalles Bibliográficos
Autores principales: Fivaz, Marc, Meyer, Tobias
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171478/
https://www.ncbi.nlm.nih.gov/pubmed/16043511
http://dx.doi.org/10.1083/jcb.200409157