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An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of endothelial cells

Clathrin provides an external scaffold to form small 50–100-nm transport vesicles. In contrast, formation of much larger dense-cored secretory granules is driven by selective aggregation of internal cargo at the trans-Golgi network; the only known role of clathrin in dense-cored secretory granules f...

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Detalles Bibliográficos
Autores principales: Lui-Roberts, Winnie W.Y., Collinson, Lucy M., Hewlett, Lindsay J., Michaux, Grégoire, Cutler, Daniel F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171491/
https://www.ncbi.nlm.nih.gov/pubmed/16087708
http://dx.doi.org/10.1083/jcb.200503054