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An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of endothelial cells
Clathrin provides an external scaffold to form small 50–100-nm transport vesicles. In contrast, formation of much larger dense-cored secretory granules is driven by selective aggregation of internal cargo at the trans-Golgi network; the only known role of clathrin in dense-cored secretory granules f...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171491/ https://www.ncbi.nlm.nih.gov/pubmed/16087708 http://dx.doi.org/10.1083/jcb.200503054 |