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An ECT2–centralspindlin complex regulates the localization and function of RhoA

In anaphase, the spindle dictates the site of contractile ring assembly. Assembly and ingression of the contractile ring involves activation of myosin-II and actin polymerization, which are triggered by the GTPase RhoA. In many cells, the central spindle affects division plane positioning via unknow...

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Detalles Bibliográficos
Autores principales: Yüce, Özlem, Piekny, Alisa, Glotzer, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171506/
https://www.ncbi.nlm.nih.gov/pubmed/16103226
http://dx.doi.org/10.1083/jcb.200501097