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PKA-catalyzed phosphorylation of tomosyn and its implication in Ca(2+)-dependent exocytosis of neurotransmitter

Neurotransmitter is released from nerve terminals by Ca(2+)-dependent exocytosis through many steps. SNARE proteins are key components at the priming and fusion steps, and the priming step is modulated by cAMP-dependent protein kinase (PKA), which causes synaptic plasticity. We show that the SNARE r...

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Detalles Bibliográficos
Autores principales: Baba, Takeshi, Sakisaka, Toshiaki, Mochida, Sumiko, Takai, Yoshimi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171531/
https://www.ncbi.nlm.nih.gov/pubmed/16186257
http://dx.doi.org/10.1083/jcb.200504055