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Selective role for superoxide in InsP(3) receptor–mediated mitochondrial dysfunction and endothelial apoptosis

Reactive oxygen species (ROS) play a divergent role in both cell survival and cell death during ischemia/reperfusion (I/R) injury and associated inflammation. In this study, ROS generation by activated macrophages evoked an intracellular Ca(2+) ([Ca(2+)](i)) transient in endothelial cells that was a...

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Detalles Bibliográficos
Autores principales: Madesh, Muniswamy, Hawkins, Brian J., Milovanova, Tatyana, Bhanumathy, Cunnigaiper D., Joseph, Suresh K., RamachandraRao, Satish P., Sharma, Kumar, Kurosaki, Tomohiro, Fisher, Aron B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171541/
https://www.ncbi.nlm.nih.gov/pubmed/16186254
http://dx.doi.org/10.1083/jcb.200505022