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Selective role for superoxide in InsP(3) receptor–mediated mitochondrial dysfunction and endothelial apoptosis
Reactive oxygen species (ROS) play a divergent role in both cell survival and cell death during ischemia/reperfusion (I/R) injury and associated inflammation. In this study, ROS generation by activated macrophages evoked an intracellular Ca(2+) ([Ca(2+)](i)) transient in endothelial cells that was a...
Autores principales: | Madesh, Muniswamy, Hawkins, Brian J., Milovanova, Tatyana, Bhanumathy, Cunnigaiper D., Joseph, Suresh K., RamachandraRao, Satish P., Sharma, Kumar, Kurosaki, Tomohiro, Fisher, Aron B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171541/ https://www.ncbi.nlm.nih.gov/pubmed/16186254 http://dx.doi.org/10.1083/jcb.200505022 |
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