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Dnm1 forms spirals that are structurally tailored to fit mitochondria

Dynamin-related proteins (DRPs) are large self-assembling GTPases whose common function is to regulate membrane dynamics in a variety of cellular processes. Dnm1, which is a yeast DRP (Drp1/Dlp1 in humans), is required for mitochondrial division, but its mechanism is unknown. We provide evidence tha...

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Detalles Bibliográficos
Autores principales: Ingerman, Elena, Perkins, Edward M., Marino, Michael, Mears, Jason A., McCaffery, J. Michael, Hinshaw, Jenny E., Nunnari, Jodi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171542/
https://www.ncbi.nlm.nih.gov/pubmed/16186251
http://dx.doi.org/10.1083/jcb.200506078