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Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

Centrosomes act as sites of microtubule growth, but little is known about how the number and stability of microtubules emanating from a centrosome are controlled during the cell cycle. We studied the role of the TACC3–XMAP215 complex in this process by using purified proteins and Xenopus laevis egg...

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Detalles Bibliográficos
Autores principales: Kinoshita, Kazuhisa, Noetzel, Tim L., Pelletier, Laurence, Mechtler, Karl, Drechsel, David N., Schwager, Anne, Lee, Mike, Raff, Jordan W., Hyman, Anthony A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171544/
https://www.ncbi.nlm.nih.gov/pubmed/16172205
http://dx.doi.org/10.1083/jcb.200503023