Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by a selective degeneration of motor neurons, atrophy, and paralysis of skeletal muscle. Although a significant proportion of familial ALS results from a toxic gain of function associated with dominant SOD1...

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Detalles Bibliográficos
Autores principales: Dobrowolny, Gabriella, Giacinti, Cristina, Pelosi, Laura, Nicoletti, Carmine, Winn, Nadine, Barberi, Laura, Molinaro, Mario, Rosenthal, Nadia, Musarò, Antonio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171577/
https://www.ncbi.nlm.nih.gov/pubmed/15657392
http://dx.doi.org/10.1083/jcb.200407021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171577/
https://www.ncbi.nlm.nih.gov/pubmed/15657392
http://dx.doi.org/10.1083/jcb.200407021

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