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ARFGAP1 plays a central role in coupling COPI cargo sorting with vesicle formation

Examining how key components of coat protein I (COPI) transport participate in cargo sorting, we find that, instead of ADP ribosylation factor 1 (ARF1), its GTPase-activating protein (GAP) plays a direct role in promoting the binding of cargo proteins by coatomer (the core COPI complex). Activated A...

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Detalles Bibliográficos
Autores principales: Lee, Stella Y., Yang, Jia-Shu, Hong, Wanjin, Premont, Richard T., Hsu, Victor W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171589/
https://www.ncbi.nlm.nih.gov/pubmed/15657398
http://dx.doi.org/10.1083/jcb.200404008