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A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleostemin
Nucleostemin (NS) was identified as a stem cell– and cancer cell–enriched nucleolar protein that controls the proliferation of these cells. Here, we report the mechanism that regulates its dynamic shuttling between the nucleolus and nucleoplasm. The nucleolar residence of nucleostemin involves a tra...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171593/ https://www.ncbi.nlm.nih.gov/pubmed/15657390 http://dx.doi.org/10.1083/jcb.200409053 |