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Methyl CpG–binding proteins induce large-scale chromatin reorganization during terminal differentiation

Pericentric heterochromatin plays an important role in epigenetic gene regulation. We show that pericentric heterochromatin aggregates during myogenic differentiation. This clustering leads to the formation of large chromocenters and correlates with increased levels of the methyl CpG–binding protein...

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Detalles Bibliográficos
Autores principales: Brero, Alessandro, Easwaran, Hariharan P., Nowak, Danny, Grunewald, Ingrid, Cremer, Thomas, Leonhardt, Heinrich, Cardoso, M. Cristina
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171616/
https://www.ncbi.nlm.nih.gov/pubmed/15939760
http://dx.doi.org/10.1083/jcb.200502062