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Methyl CpG–binding proteins induce large-scale chromatin reorganization during terminal differentiation
Pericentric heterochromatin plays an important role in epigenetic gene regulation. We show that pericentric heterochromatin aggregates during myogenic differentiation. This clustering leads to the formation of large chromocenters and correlates with increased levels of the methyl CpG–binding protein...
Autores principales: | Brero, Alessandro, Easwaran, Hariharan P., Nowak, Danny, Grunewald, Ingrid, Cremer, Thomas, Leonhardt, Heinrich, Cardoso, M. Cristina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171616/ https://www.ncbi.nlm.nih.gov/pubmed/15939760 http://dx.doi.org/10.1083/jcb.200502062 |
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