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G protein β interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus

Extracellular stimuli that activate cell surface receptors modulate glucocorticoid actions via as yet unclear mechanisms. Here, we report that the guanine nucleotide-binding protein (G protein)–coupled receptor-activated WD-repeat Gβ interacts with the glucocorticoid receptor (GR), comigrates with i...

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Detalles Bibliográficos
Autores principales: Kino, Tomoshige, Tiulpakov, Anatoly, Ichijo, Takamasa, Chheng, Ly, Kozasa, Tohru, Chrousos, George P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171637/
https://www.ncbi.nlm.nih.gov/pubmed/15955845
http://dx.doi.org/10.1083/jcb.200409150