Cargando…
G protein β interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus
Extracellular stimuli that activate cell surface receptors modulate glucocorticoid actions via as yet unclear mechanisms. Here, we report that the guanine nucleotide-binding protein (G protein)–coupled receptor-activated WD-repeat Gβ interacts with the glucocorticoid receptor (GR), comigrates with i...
Autores principales: | Kino, Tomoshige, Tiulpakov, Anatoly, Ichijo, Takamasa, Chheng, Ly, Kozasa, Tohru, Chrousos, George P. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171637/ https://www.ncbi.nlm.nih.gov/pubmed/15955845 http://dx.doi.org/10.1083/jcb.200409150 |
Ejemplares similares
-
Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor
por: Nicolaides, Nicolas C, et al.
Publicado: (2014) -
Liver X Receptors Regulate the Transcriptional Activity of the Glucocorticoid Receptor: Implications for the Carbohydrate Metabolism
por: Nader, Nancy, et al.
Publicado: (2012) -
Stress-Related and Circadian Secretion and Target Tissue Actions of Glucocorticoids: Impact on Health
por: Nicolaides, Nicolas C., et al.
Publicado: (2017) -
Peripheral CLOCK Regulates Target-Tissue Glucocorticoid Receptor Transcriptional Activity in a Circadian Fashion in Man
por: Charmandari, Evangelia, et al.
Publicado: (2011) -
The HIV-1 Virion-associated Protein Vpr Is a Coactivator of the Human Glucocorticoid Receptor
por: Kino, Tomoshige, et al.
Publicado: (1999)