Cargando…

The PSD95–nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death

The stress-activated protein kinase p38 and nitric oxide (NO) are proposed downstream effectors of excitotoxic cell death. Although the postsynaptic density protein PSD95 can recruit the calcium-dependent neuronal NO synthase (nNOS) to the mouth of the calcium-permeable NMDA receptor, and depletion...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Jiong, Viholainen, Jenni I., Dart, Caroline, Warwick, Helen K., Leyland, Mark L., Courtney, Michael J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171658/
https://www.ncbi.nlm.nih.gov/pubmed/15631993
http://dx.doi.org/10.1083/jcb.200407024