Cargando…

MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A

Cell cycle exit is required for proper differentiation in most cells and is critical for normal development, tissue homeostasis, and tumor suppression. However, the mechanisms that link cell cycle exit with differentiation remain poorly understood. Here, we show that the master melanocyte differenti...

Descripción completa

Detalles Bibliográficos
Autores principales: Loercher, Amy E., Tank, Elizabeth M.H., Delston, Rachel B., Harbour, J. William
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171666/
https://www.ncbi.nlm.nih.gov/pubmed/15623583
http://dx.doi.org/10.1083/jcb.200410115