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MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A
Cell cycle exit is required for proper differentiation in most cells and is critical for normal development, tissue homeostasis, and tumor suppression. However, the mechanisms that link cell cycle exit with differentiation remain poorly understood. Here, we show that the master melanocyte differenti...
Autores principales: | Loercher, Amy E., Tank, Elizabeth M.H., Delston, Rachel B., Harbour, J. William |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171666/ https://www.ncbi.nlm.nih.gov/pubmed/15623583 http://dx.doi.org/10.1083/jcb.200410115 |
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