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Specialized membrane-localized chaperones prevent aggregation of polytopic proteins in the ER
The integral endoplasmic reticulum (ER) membrane protein Shr3p is required for proper plasma membrane localization of amino acid permeases (AAPs) in yeast. In the absence of Shr3p AAPs are uniquely retained in the ER with each of their twelve membrane-spanning segments correctly inserted in the memb...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171667/ https://www.ncbi.nlm.nih.gov/pubmed/15623581 http://dx.doi.org/10.1083/jcb.200408106 |