HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway

Many enveloped viruses exploit the class E vacuolar protein-sorting (VPS) pathway to bud from cells, and use peptide motifs to recruit specific class E VPS factors. Homologous to E6AP COOH terminus (HECT) ubiquitin ligases have been implicated as cofactors for PPXY motif–dependent budding, but preci...

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Detalles Bibliográficos
Autores principales: Martin-Serrano, Juan, Eastman, Scott W., Chung, Wayne, Bieniasz, Paul D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171676/
https://www.ncbi.nlm.nih.gov/pubmed/15623582
http://dx.doi.org/10.1083/jcb.200408155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171676/
https://www.ncbi.nlm.nih.gov/pubmed/15623582
http://dx.doi.org/10.1083/jcb.200408155

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