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Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation
The cytoplasmic surface of Sec61p is the binding site for the ribosome and has been proposed to interact with the signal recognition particle receptor during targeting of the ribosome nascent chain complex to the translocation channel. Point mutations in cytoplasmic loops six (L6) and eight (L8) of...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171681/ https://www.ncbi.nlm.nih.gov/pubmed/15631991 http://dx.doi.org/10.1083/jcb.200408188 |