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Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins

During mitosis, chromosomes are highly condensed and transcription is silenced globally. One explanation for transcriptional repression is the reduced accessibility of transcription factors. To directly test this hypothesis and to investigate the dynamics of mitotic chromatin, we evaluate the exchan...

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Detalles Bibliográficos
Autores principales: Chen, Danyang, Dundr, Miroslav, Wang, Chen, Leung, Anthony, Lamond, Angus, Misteli, Tom, Huang, Sui
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171683/
https://www.ncbi.nlm.nih.gov/pubmed/15623580
http://dx.doi.org/10.1083/jcb.200407182