Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial–mesenchymal transition

We report that the activity of glycogen synthase kinase-3 (GSK-3) is necessary for the maintenance of the epithelial architecture. Pharmacological inhibition of its activity or reducing its expression using small interfering RNAs in normal breast and skin epithelial cells results in a reduction of E...

Descripción completa

Detalles Bibliográficos
Autores principales: Bachelder, Robin E., Yoon, Sang-Oh, Franci, Clara, de Herreros, Antonio García, Mercurio, Arthur M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171685/
https://www.ncbi.nlm.nih.gov/pubmed/15631989
http://dx.doi.org/10.1083/jcb.200409067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171685/
https://www.ncbi.nlm.nih.gov/pubmed/15631989
http://dx.doi.org/10.1083/jcb.200409067

Ejemplares similares