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Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain

Timely differentiation of progenitor cells is critical for development. In this study we asked whether global epigenetic mechanisms regulate timing of progenitor cell differentiation into myelin-forming oligodendrocytes in vivo. Histone deacetylation was essential during a specific temporal window o...

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Detalles Bibliográficos
Autores principales: Shen, Siming, Li, Jiadong, Casaccia-Bonnefil, Patrizia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171688/
https://www.ncbi.nlm.nih.gov/pubmed/15897262
http://dx.doi.org/10.1083/jcb.200412101