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Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
Timely differentiation of progenitor cells is critical for development. In this study we asked whether global epigenetic mechanisms regulate timing of progenitor cell differentiation into myelin-forming oligodendrocytes in vivo. Histone deacetylation was essential during a specific temporal window o...
Autores principales: | Shen, Siming, Li, Jiadong, Casaccia-Bonnefil, Patrizia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171688/ https://www.ncbi.nlm.nih.gov/pubmed/15897262 http://dx.doi.org/10.1083/jcb.200412101 |
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