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Endoplasmic reticulum stress signaling transmitted by ATF6 mediates apoptosis during muscle development

Although apoptosis occurs during myogenesis, its mechanism of initiation remains unknown. In a culture model, we demonstrate activation of caspase-12, the initiator of the endoplasmic reticulum (ER) stress-specific caspase cascade, during apoptosis associated with myoblast differentiation. Induction...

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Detalles Bibliográficos
Autores principales: Nakanishi, Keiko, Sudo, Tatsuhiko, Morishima, Nobuhiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171703/
https://www.ncbi.nlm.nih.gov/pubmed/15897261
http://dx.doi.org/10.1083/jcb.200412024