Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors

Vascular endothelial growth factor (VEGF) is a critical mediator of blood vessel formation during development and in pathological conditions. In this study, we demonstrate that VEGF bioavailability is regulated extracellularly by matrix metalloproteinases (MMPs) through intramolecular processing. Sp...

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Detalles Bibliográficos
Autores principales: Lee, Sunyoung, Jilani, Shahla M., Nikolova, Ganka V., Carpizo, Darren, Iruela-Arispe, M. Luisa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171712/
https://www.ncbi.nlm.nih.gov/pubmed/15911882
http://dx.doi.org/10.1083/jcb.200409115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171712/
https://www.ncbi.nlm.nih.gov/pubmed/15911882
http://dx.doi.org/10.1083/jcb.200409115

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