Molecular mechanisms of invadopodium formation: the role of the N-WASP–Arp2/3 complex pathway and cofilin

Invadopodia are actin-rich membrane protrusions with a matrix degradation activity formed by invasive cancer cells. We have studied the molecular mechanisms of invadopodium formation in metastatic carcinoma cells. Epidermal growth factor (EGF) receptor kinase inhibitors blocked invadopodium formatio...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Hideki, Lorenz, Mike, Kempiak, Stephan, Sarmiento, Corina, Coniglio, Salvatore, Symons, Marc, Segall, Jeffrey, Eddy, Robert, Miki, Hiroaki, Takenawa, Tadaomi, Condeelis, John
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171731/
https://www.ncbi.nlm.nih.gov/pubmed/15684033
http://dx.doi.org/10.1083/jcb.200407076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171731/
https://www.ncbi.nlm.nih.gov/pubmed/15684033
http://dx.doi.org/10.1083/jcb.200407076

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