Cargando…

Molecular mechanisms of invadopodium formation: the role of the N-WASP–Arp2/3 complex pathway and cofilin

Invadopodia are actin-rich membrane protrusions with a matrix degradation activity formed by invasive cancer cells. We have studied the molecular mechanisms of invadopodium formation in metastatic carcinoma cells. Epidermal growth factor (EGF) receptor kinase inhibitors blocked invadopodium formatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamaguchi, Hideki, Lorenz, Mike, Kempiak, Stephan, Sarmiento, Corina, Coniglio, Salvatore, Symons, Marc, Segall, Jeffrey, Eddy, Robert, Miki, Hiroaki, Takenawa, Tadaomi, Condeelis, John
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171731/ https://www.ncbi.nlm.nih.gov/pubmed/15684033 http://dx.doi.org/10.1083/jcb.200407076

Ejemplares similares

Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
por: Oser, Matthew, et al.
Publicado: (2009)

A Novel Neural Wiskott-Aldrich Syndrome Protein (N-Wasp) Binding Protein, Wish, Induces Arp2/3 Complex Activation Independent of Cdc42
por: Fukuoka, Maiko, et al.
Publicado: (2001)

The WASP and WAVE family proteins
por: Kurisu, Shusaku, et al.
Publicado: (2009)

Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation
por: Weidmann, Maxwell D., et al.
Publicado: (2016)

VCA nanobodies target N-WASp to reduce invadopodium formation and functioning
por: Hebbrecht, Tim, et al.
Publicado: (2017)

Role of Cofilin in Epidermal Growth Factor–Stimulated Actin Polymerization and Lamellipod Protrusion
por: Chan, Amanda Y., et al.
Publicado: (2000)

Cofilin determines the migration behavior and turning frequency of metastatic cancer cells
por: Sidani, Mazen, et al.
Publicado: (2007)

Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/Mena(INV)-initiated invadopodium formation
por: Pignatelli, Jeanine, et al.
Publicado: (2016)

srGAP1 regulates lamellipodial dynamics and cell migratory behavior by modulating Rac1 activity
por: Yamazaki, Daisuke, et al.
Publicado: (2013)

WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells
por: Sarmiento, Corina, et al.
Publicado: (2008)

PI(3,4)P(2) plays critical roles in the regulation of focal adhesion dynamics of MDA‐MB‐231 breast cancer cells
por: Fukumoto, Miki, et al.
Publicado: (2017)

Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis
por: Hernandez, Lorena, et al.
Publicado: (2011)

VEGF Triggers the Activation of Cofilin and the Arp2/3 Complex within the Growth Cone
por: Schlau, Matthias, et al.
Publicado: (2018)

Phosphoinositide-binding interface proteins involved in shaping cell membranes
por: TAKENAWA, Tadaomi
Publicado: (2010)

Relationship between Arp2/3 Complex and the Barbed Ends of Actin Filaments at the Leading Edge of Carcinoma Cells after Epidermal Growth Factor Stimulation
por: Bailly, Maryse, et al.
Publicado: (1999)

α-Actinin-4 Enhances Colorectal Cancer Cell Invasion by Suppressing Focal Adhesion Maturation
por: Fukumoto, Miki, et al.
Publicado: (2015)

WASP family proteins, more than Arp2/3 activators
por: Tyler, Joe J., et al.
Publicado: (2016)

Phosphoinositide 3-kinase p85beta regulates invadopodium formation
por: Cariaga-Martínez, Ariel E., et al.
Publicado: (2014)

Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin
por: Koestler, Stefan A., et al.
Publicado: (2013)

Mechanism of synergistic activation of Arp2/3 complex by cortactin and N-WASP
por: Helgeson, Luke A, et al.
Publicado: (2013)

Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation
por: Mouneimne, Ghassan, et al.
Publicado: (2004)

Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins
por: Fregoso, Fred E., et al.
Publicado: (2023)

Rho Family Gtpase Cdc42 Is Essential for the Actin-Based Motility of Shigella in Mammalian Cells
por: Suzuki, Toshihiko, et al.
Publicado: (2000)

Targeting SNARE-Mediated Vesicle Transport to Block Invadopodium-Based Cancer Cell Invasion
por: Gorshtein, Genya, et al.
Publicado: (2021)

Optogenetic control of Cofilin and αTAT in living cells using Z-lock
por: Stone, Orrin J., et al.
Publicado: (2019)

Activation of Arp2/3 Complex: Addition of the First Subunit of the New Filament by a WASP Protein Triggers Rapid ATP Hydrolysis on Arp2
por: Dayel, Mark J, et al.
Publicado: (2004)

Arp2/3 Complex and Actin Depolymerizing Factor/Cofilin in Dendritic Organization and Treadmilling of Actin Filament Array in Lamellipodia
por: Svitkina, Tatyana M., et al.
Publicado: (1999)

WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility
por: Howell, Michael, et al.
Publicado: (2015)

Regulation of CD44 expression and focal adhesion by Golgi phosphatidylinositol 4‐phosphate in breast cancer
por: Ijuin, Takeshi, et al.
Publicado: (2016)

Sequential signals toward podosome formation in NIH-src cells
por: Oikawa, Tsukasa, et al.
Publicado: (2008)

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding
por: Frantz, Christian, et al.
Publicado: (2008)

Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway
por: Bompard, Guillaume, et al.
Publicado: (2008)

Regulation of N-WASP and the Arp2/3 Complex by Abp1 Controls Neuronal Morphology
por: Pinyol, Roser, et al.
Publicado: (2007)

Evolution of the eukaryotic ARP2/3 activators of the WASP family: WASP, WAVE, WASH, and WHAMM, and the proposed new family members WAWH and WAML
por: Kollmar, Martin, et al.
Publicado: (2012)

EGF-induced PIP(2) hydrolysis releases and activates cofilin locally in carcinoma cells
por: van Rheenen, Jacco, et al.
Publicado: (2007)

Microglial-stimulation of glioma invasion involves the EGFR ligand amphiregulin
por: Coniglio, Salvatore J., et al.
Publicado: (2021)

Profilin Enhances Cdc42-Induced Nucleation of Actin Polymerization
por: Yang, Changsong, et al.
Publicado: (2000)

Arp2/3- and Cofilin-coordinated Actin Dynamics Is Required for Insulin-mediated GLUT4 Translocation to the Surface of Muscle Cells
por: Chiu, Tim Ting, et al.
Publicado: (2010)

STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion
por: Sun, Jianwei, et al.
Publicado: (2014)

Local signaling by the EGF receptor
por: Kempiak, Stephan J., et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_qstk7sc2fgkqc6e8u4m3ftjrkl