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L1, a novel target of β-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers

Aberrant β-catenin-TCF target gene activation plays a key role in colorectal cancer, both in the initiation stage and during invasion and metastasis. We identified the neuronal cell adhesion molecule L1, as a target gene of β-catenin-TCF signaling in colorectal cancer cells. L1 expression was high i...

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Detalles Bibliográficos
Autores principales: Gavert, Nancy, Conacci-Sorrell, Maralice, Gast, Daniela, Schneider, Annette, Altevogt, Peter, Brabletz, Thomas, Ben-Ze'ev, Avri
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171754/
https://www.ncbi.nlm.nih.gov/pubmed/15716380
http://dx.doi.org/10.1083/jcb.200408051