Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by β(1) integrins

The anti-angiogenic effect of thrombospondin-1 has been shown to be mediated through binding of the type-1 repeat (TSR) domain to the CD36 transmembrane receptor. We now report that the TSR domain can inhibit VEGF-induced migration in human umbilical vein endothelial cells (HUVEC), cells that lack C...

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Detalles Bibliográficos
Autores principales: Short, Sarah M., Derrien, Alexandrine, Narsimhan, Radha P., Lawler, Jack, Ingber, Donald E., Zetter, Bruce R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171765/
https://www.ncbi.nlm.nih.gov/pubmed/15716381
http://dx.doi.org/10.1083/jcb.200407060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171765/
https://www.ncbi.nlm.nih.gov/pubmed/15716381
http://dx.doi.org/10.1083/jcb.200407060

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