Chromatin decondensation in S-phase involves recruitment of Cdk2 by Cdc45 and histone H1 phosphorylation

Cdc45 is required for initiation of DNA replication and fork progression, but its function in these processes remains unknown. We show that targeting Cdc45 to specific chromosomal sites in mammalian cells results in large-scale chromatin decondensation that strongly correlates with histone H1 phosph...

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Detalles Bibliográficos
Autores principales: Alexandrow, Mark G., Hamlin, Joyce L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171796/
https://www.ncbi.nlm.nih.gov/pubmed/15753125
http://dx.doi.org/10.1083/jcb.200409055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171796/
https://www.ncbi.nlm.nih.gov/pubmed/15753125
http://dx.doi.org/10.1083/jcb.200409055

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