β1 integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation

We previously demonstrated that integrin-dependent adhesion activates STAT5A, a well known target of IL-3–mediated signaling. Here, we show that in endothelial cells the active β1 integrin constitutively associates with the unphosphorylated IL-3 receptor (IL-3R) β common subunit. This association is...

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Detalles Bibliográficos
Autores principales: Defilippi, Paola, Rosso, Arturo, Dentelli, Patrizia, Calvi, Cristina, Garbarino, Giovanni, Tarone, Guido, Pegoraro, Luigi, Brizzi, Maria Felice
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171831/
https://www.ncbi.nlm.nih.gov/pubmed/15795318
http://dx.doi.org/10.1083/jcb.200405116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171831/
https://www.ncbi.nlm.nih.gov/pubmed/15795318
http://dx.doi.org/10.1083/jcb.200405116

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