Cargando…
β1 integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation
We previously demonstrated that integrin-dependent adhesion activates STAT5A, a well known target of IL-3–mediated signaling. Here, we show that in endothelial cells the active β1 integrin constitutively associates with the unphosphorylated IL-3 receptor (IL-3R) β common subunit. This association is...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171831/ https://www.ncbi.nlm.nih.gov/pubmed/15795318 http://dx.doi.org/10.1083/jcb.200405116 |