The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability

Using fluorescent variants of Fas and FasL, we show that membrane FasL and Fas form supramolecular clusters that are of flexible shape, but nevertheless stable and persistent. Membrane FasL-induced Fas clusters were formed in caspase-8– or FADD-deficient cells or when a cytoplasmic deletion mutant o...

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Detalles Bibliográficos
Autores principales: Henkler, Frank, Behrle, Eva, Dennehy, Kevin M., Wicovsky, Andreas, Peters, Nathalie, Warnke, Clemens, Pfizenmaier, Klaus, Wajant, Harald
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171833/
https://www.ncbi.nlm.nih.gov/pubmed/15795317
http://dx.doi.org/10.1083/jcb.200501048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171833/
https://www.ncbi.nlm.nih.gov/pubmed/15795317
http://dx.doi.org/10.1083/jcb.200501048

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