Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin

Integrins are αβ heterodimeric cell surface receptors that mediate transmembrane signaling by binding extracellular and cytoplasmic ligands. The ectodomain of integrin αVβ3 crystallizes in a bent, genuflexed conformation considered to be inactive (unable to bind physiological ligands in solution) un...

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Detalles Bibliográficos
Autores principales: Adair, Brian D., Xiong, Jian-Ping, Maddock, Catherine, Goodman, Simon L., Arnaout, M. Amin, Yeager, Mark
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171847/
https://www.ncbi.nlm.nih.gov/pubmed/15795319
http://dx.doi.org/10.1083/jcb.200410068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171847/
https://www.ncbi.nlm.nih.gov/pubmed/15795319
http://dx.doi.org/10.1083/jcb.200410068

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