eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3′UTR

The eukaryotic translation initiation factor eIF4E is a critical modulator of cellular growth with functions in the nucleus and cytoplasm. In the cytoplasm, recognition of the 5′ m(7)G cap moiety on all mRNAs is sufficient for their functional interaction with eIF4E. In contrast, we have shown that...

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Detalles Bibliográficos
Autores principales: Culjkovic, Biljana, Topisirovic, Ivan, Skrabanek, Lucy, Ruiz-Gutierrez, Melisa, Borden, Katherine L.B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171863/
https://www.ncbi.nlm.nih.gov/pubmed/15837800
http://dx.doi.org/10.1083/jcb.200501019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171863/
https://www.ncbi.nlm.nih.gov/pubmed/15837800
http://dx.doi.org/10.1083/jcb.200501019

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