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Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59(fyn) and to enhance neurite outgrowth
In spite of advances in understanding the role of the cellular prion protein (PrP) in neural cell interactions, the mechanisms of PrP function remain poorly characterized. We show that PrP interacts directly with the neural cell adhesion molecule (NCAM) and associates with NCAM at the neuronal cell...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171870/ https://www.ncbi.nlm.nih.gov/pubmed/15851519 http://dx.doi.org/10.1083/jcb.200409127 |