Cargando…

Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59(fyn) and to enhance neurite outgrowth

In spite of advances in understanding the role of the cellular prion protein (PrP) in neural cell interactions, the mechanisms of PrP function remain poorly characterized. We show that PrP interacts directly with the neural cell adhesion molecule (NCAM) and associates with NCAM at the neuronal cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santuccione, Antonella, Sytnyk, Vladimir, Leshchyns'ka, Iryna, Schachner, Melitta
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171870/ https://www.ncbi.nlm.nih.gov/pubmed/15851519 http://dx.doi.org/10.1083/jcb.200409127

Ejemplares similares

RPTPα is essential for NCAM-mediated p59(fyn) activation and neurite elongation
por: Bodrikov, Vsevolod, et al.
Publicado: (2005)

Neural cell adhesion molecule (NCAM) association with PKCβ(2) via βI spectrin is implicated in NCAM-mediated neurite outgrowth
por: Leshchyns'ka, Iryna, et al.
Publicado: (2003)

NCAM induces CaMKIIα-mediated RPTPα phosphorylation to enhance its catalytic activity and neurite outgrowth
por: Bodrikov, Vsevolod, et al.
Publicado: (2008)

NCAM promotes assembly and activity-dependent remodeling of the postsynaptic signaling complex
por: Sytnyk, Vladimir, et al.
Publicado: (2006)

NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice
Publicado: (1994)

Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis
por: Niethammer, Philipp, et al.
Publicado: (2002)

The BACE1-generated C-terminal fragment of the neural cell adhesion molecule 2 (NCAM2) promotes BACE1 targeting to Rab11-positive endosomes
por: Keable, Ryan, et al.
Publicado: (2022)

Neural cell adhesion molecule promotes accumulation of TGN organelles at sites of neuron-to-neuron contacts
por: Sytnyk, Vladimir, et al.
Publicado: (2002)

CHL1 Is a Selective Organizer of the Presynaptic Machinery Chaperoning the SNARE Complex
por: Andreyeva, Aksana, et al.
Publicado: (2010)

Cell Adhesion Molecule Close Homolog of L1 (CHL1) Guides the Regrowth of Regenerating Motor Axons and Regulates Synaptic Coverage of Motor Neurons
por: Guseva, Daria, et al.
Publicado: (2018)

Reciprocal Interactions between Cell Adhesion Molecules of the Immunoglobulin Superfamily and the Cytoskeleton in Neurons
por: Leshchyns'ka, Iryna, et al.
Publicado: (2016)

Synaptic Cell Adhesion Molecules in Alzheimer's Disease
por: Leshchyns'ka, Iryna, et al.
Publicado: (2016)

Cell adhesion and intracellular calcium signaling in neurons
por: Sheng, Lifu, et al.
Publicado: (2013)

Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease
por: Leshchyns'ka, Iryna, et al.
Publicado: (2015)

Glycosylphosphatidylinositol-Anchored Immunoglobulin Superfamily Cell Adhesion Molecules and Their Role in Neuronal Development and Synapse Regulation
por: Tan, Rui P. A., et al.
Publicado: (2017)

N-cadherin, NCAM, and integrins promote retinal neurite outgrowth on astrocytes in vitro
Publicado: (1988)

Cell Adhesion Molecules and Protein Synthesis Regulation in Neurons
por: Kozlova, Irina, et al.
Publicado: (2020)

Expression of NCAM containing VASE in neurons can account for a developmental loss in their neurite outgrowth response to NCAM in a cellular substratum
Publicado: (1994)

Interaction of L1CAM with LC3 Is Required for L1-Dependent Neurite Outgrowth and Neuronal Survival
por: Loers, Gabriele, et al.
Publicado: (2023)

Small Organic Compounds Mimicking the Effector Domain of Myristoylated Alanine-Rich C-Kinase Substrate Stimulate Female-Specific Neurite Outgrowth
por: Tschang, Monica, et al.
Publicado: (2023)

Application of Antibodies to Neuronally Expressed Nogo-A Increases Neuronal Survival and Neurite Outgrowth
por: Nagaraj, Vini, et al.
Publicado: (2020)

NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesis
por: Huang, Rui, et al.
Publicado: (2019)

The fourth immunoglobulin-like domain of NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth
Publicado: (1993)

Nuclear fragments of the neural cell adhesion molecule NCAM with or without polysialic acid differentially regulate gene expression
por: Westphal, Nina, et al.
Publicado: (2017)

The 14-3-3ζ Protein Binds to the Cell Adhesion Molecule L1, Promotes L1 Phosphorylation by CKII and Influences L1-Dependent Neurite Outgrowth
por: Ramser, Elisa M., et al.
Publicado: (2010)

Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts
por: Filipp, Dominik, et al.
Publicado: (2003)

Recruitment of cellular prion protein to mitochondrial raft-like microdomains contributes to apoptosis execution
por: Mattei, Vincenzo, et al.
Publicado: (2011)

Generation and intracellular trafficking of a polysialic acid-carrying fragment of the neural cell adhesion molecule NCAM to the cell nucleus
por: Westphal, Nina, et al.
Publicado: (2017)

Cell Surface Sialylation and Fucosylation Are Regulated by L1 via Phospholipase Cγ and Cooperate to Modulate Neurite Outgrowth, Cell Survival and Migration
por: Li, Ya-li, et al.
Publicado: (2008)

NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?
por: Mehrabian, Mohadeseh, et al.
Publicado: (2016)

T cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T)
Publicado: (1993)

Neurite Outgrowth Inhibitors in Gliotic Tissue
por: Nieto-Sampedro, M., et al.
Publicado: (1992)

The impact of resource competition on neurite outgrowth
por: Hjorth, Johannes JJ, et al.
Publicado: (2011)

Proteoglycans: Road Signs for Neurite Outgrowth
por: Beller, Justin A., et al.
Publicado: (2014)

An Integrated Cytoskeletal Model of Neurite Outgrowth
por: Miller, Kyle E., et al.
Publicado: (2018)

Lactate transport facilitates neurite outgrowth
por: Chen, Kun, et al.
Publicado: (2018)

Ultrasonic control of neurite outgrowth direction
por: Maruyama, Haruki, et al.
Publicado: (2021)

ARNO is recruited by the neuronal adaptor FE65 to potentiate ARF6-mediated neurite outgrowth
por: Zhai, Yuqi, et al.
Publicado: (2022)

The Effects of Hematopoietic Growth Factors on Neurite Outgrowth
por: Su, Ye, et al.
Publicado: (2013)

Inducing Neurite Outgrowth by Mechanical Cell Stretch
por: Higgins, Suzanne, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_5i5ihrfn60j66i8fq3qdjgvrrp