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Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator

X-linked adrenoleukodystrophy (X-ALD) is a demyelinating disease due to mutations in the ABCD1 (ALD) gene, encoding a peroxisomal ATP-binding cassette transporter (ALDP). Overexpression of adrenoleukodystrophy-related protein, an ALDP homologue encoded by the ABCD2 (adrenoleukodystrophy-related) gen...

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Detalles Bibliográficos
Autores principales: Gondcaille, Catherine, Depreter, Marianne, Fourcade, Stéphane, Lecca, Maria Rita, Leclercq, Sabrina, Martin, Pascal G.P., Pineau, Thierry, Cadepond, Françoise, ElEtr, Martine, Bertrand, Nathalie, Beley, Alain, Duclos, Sandrine, De Craemer, Dirk, Roels, Frank, Savary, Stéphane, Bugaut, Maurice
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171887/
https://www.ncbi.nlm.nih.gov/pubmed/15809314
http://dx.doi.org/10.1083/jcb.200501036