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Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator
X-linked adrenoleukodystrophy (X-ALD) is a demyelinating disease due to mutations in the ABCD1 (ALD) gene, encoding a peroxisomal ATP-binding cassette transporter (ALDP). Overexpression of adrenoleukodystrophy-related protein, an ALDP homologue encoded by the ABCD2 (adrenoleukodystrophy-related) gen...
Autores principales: | Gondcaille, Catherine, Depreter, Marianne, Fourcade, Stéphane, Lecca, Maria Rita, Leclercq, Sabrina, Martin, Pascal G.P., Pineau, Thierry, Cadepond, Françoise, ElEtr, Martine, Bertrand, Nathalie, Beley, Alain, Duclos, Sandrine, De Craemer, Dirk, Roels, Frank, Savary, Stéphane, Bugaut, Maurice |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171887/ https://www.ncbi.nlm.nih.gov/pubmed/15809314 http://dx.doi.org/10.1083/jcb.200501036 |
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