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Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation
The endoplasmic reticulum (ER) maintains an environment essential for secretory protein folding. Consequently, the premature transport of polypeptides would be harmful to the cell. To avert this scenario, mechanisms collectively termed “ER quality control” prevent the transport of nascent polypeptid...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171888/ https://www.ncbi.nlm.nih.gov/pubmed/15809311 http://dx.doi.org/10.1083/jcb.200411136 |