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Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis

The Rho GTPases play a critical role in initiating actin polymerization during phagocytosis. In contrast, the factors directing the disassembly of F-actin required for fission of the phagocytic vacuole are ill defined. We used fluorescent chimeric proteins to monitor the dynamics of association of a...

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Detalles Bibliográficos
Autores principales: Scott, Cameron C., Dobson, Wendy, Botelho, Roberto J., Coady-Osberg, Natasha, Chavrier, Philippe, Knecht, David A., Heath, Colin, Stahl, Philip, Grinstein, Sergio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171893/
https://www.ncbi.nlm.nih.gov/pubmed/15809313
http://dx.doi.org/10.1083/jcb.200412162