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PKCη is required for β1γ2/β3γ2- and PKD-mediated transport to the cell surface and the organization of the Golgi apparatus
Protein kinase D (PKD) binds to a pool of diacylglycerol (DAG) in the TGN and undergoes a process of activation that involves heterotrimeric GTP-binding protein subunits βγ to regulate membrane fission. This fission reaction is used to generate transport carriers at the TGN that are en route to the...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171908/ https://www.ncbi.nlm.nih.gov/pubmed/15824133 http://dx.doi.org/10.1083/jcb.200412089 |