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Promotion of importin α–mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3

14-3-3 proteins are phosphoserine/threonine-binding proteins that play important roles in many regulatory processes, including intracellular protein targeting. 14-3-3 proteins can anchor target proteins in the cytoplasm and in the nucleus or can mediate their nuclear export. So far, no role for 14-3...

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Detalles Bibliográficos
Autores principales: Faul, Christian, Hüttelmaier, Stefan, Oh, Jun, Hachet, Virginie, Singer, Robert H., Mundel, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171942/
https://www.ncbi.nlm.nih.gov/pubmed/15883195
http://dx.doi.org/10.1083/jcb.200411169