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Greatwall kinase: a nuclear protein required for proper chromosome condensation and mitotic progression in Drosophila
Mutations in the Drosophila gene greatwall cause improper chromosome condensation and delay cell cycle progression in larval neuroblasts. Chromosomes are highly undercondensed, particularly in the euchromatin, but nevertheless contain phosphorylated histone H3, condensin, and topoisomerase II. Cells...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171981/ https://www.ncbi.nlm.nih.gov/pubmed/14970188 http://dx.doi.org/10.1083/jcb.200310059 |