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CD44 modulates Smad1 activation in the BMP-7 signaling pathway

Bone morphogenetic protein 7 (BMP-7) regulates cellular metabolism in embryonic and adult tissues. Signal transduction occurs through the activation of intracellular Smad proteins. In this paper, using a yeast two-hybrid screen, Smad1 was found to interact with the cytoplasmic domain of CD44, a rece...

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Detalles Bibliográficos
Autores principales: Peterson, Richard S., Andhare, Roma A., Rousche, Kathleen T., Knudson, Warren, Wang, Weihua, Grossfield, Jami B., Thomas, Raymond O., Hollingsworth, Robert E., Knudson, Cheryl B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172010/
https://www.ncbi.nlm.nih.gov/pubmed/15452148
http://dx.doi.org/10.1083/jcb.200402138