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Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

Presenilin 1 (PS1) interacts with telencephalin (TLN) and the amyloid precursor protein via their transmembrane domain (Annaert, W.G., C. Esselens, V. Baert, C. Boeve, G. Snellings, P. Cupers, K. Craessaerts, and B. De Strooper. 2001. Neuron. 32:579–589). Here, we demonstrate that TLN is not a subst...

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Detalles Bibliográficos
Autores principales: Esselens, Cary, Oorschot, Viola, Baert, Veerle, Raemaekers, Tim, Spittaels, Kurt, Serneels, Lutgarde, Zheng, Hui, Saftig, Paul, De Strooper, Bart, Klumperman, Judith, Annaert, Wim
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172014/
https://www.ncbi.nlm.nih.gov/pubmed/15452145
http://dx.doi.org/10.1083/jcb.200406060